DiSodium EDTA
1. Key Characteristics
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Appearance: White crystalline powder
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Solubility: Highly soluble in water (≈50 g/100 mL at 20°C)
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pH (1% solution): 4.0–5.5
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Chelation Strength: Binds divalent metal ions (e.g., Ca²⁺, Mg²⁺, Fe²⁺)
2. Common Applications
Cosmetics & Personal Care
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Function: Preservative stabilizer, chelates metal ions to prevent spoilage.
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Found In: Shampoos, creams, soaps.
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Max Concentration: Typically 0.1–0.3%.
Food Industry
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Function: Antioxidant synergist (prevents oxidation by metal ions).
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Approvals: FDA-approved (21 CFR 172.135) for limited uses (e.g., dressings, canned foods).
Pharmaceuticals
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Function: Anticoagulant (in blood collection tubes), stabilizer in injections.
Industrial/Water Treatment
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Function: Scale inhibitor, boiler water additive.
3. Safety & Handling
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Storage: Cool, dry place; keep container tightly sealed.
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Skin Contact: Mild irritant—rinse with water.
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Ingestion: Seek medical attention (may bind essential minerals).
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Environmental Impact: Biodegradable but can mobilize heavy metals in water.
4. Regulatory Compliance
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EU Cosmetics Regulation (EC 1223/2009): Allowed (up to 0.2% in rinse-off products).
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US FDA: GRAS (Generally Recognized as Safe) for specific food uses.
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REACH: Registered under EC 1907/2006.
5. Frequently Asked Questions (FAQs)
Q: Is Disodium EDTA safe in skincare?
A: Yes, in low concentrations (<0.3%). It’s non-toxic but may cause irritation in sensitive skin.